A case of apogeotropic nystagmus with brainstem lesion: An implication for mechanism of central apogeotropic nystagmus

We report a case showing apogeotropic nystagmus with the lesion of the brain stem, and discuss a possible mechanism of central apogeotropic nystagmus. The case was a 73-year-old male. We analyzed his nystagmus three-dimensionally. He showed apogeotropic nystagmus. Axis angles of slow phase eye velocity of his apogeotropic nystagmus were not in line with the axes perpendicular to the plane of horizontal semicircular canals, but with the patient's vertical axis. We then found that his nystagmus including the apogeotropic nystagmus was positioning, but not positional and that the direction of his positioning nystagmus was the same direction of postrotatory nystagmus after his head movement. His MRI scans showed an infarction around the prepositus hypoglossi nucleus of the brain. His apogeotropic nystagmus seemed to consist of a combination of prolonged postrotatory nystagmus after his head rotation to the left and right lateral position because the axis of postrotatory nystamus was in line with the axis of the head rotation. Therefore, it is suggested that a possible mechanism of central apogeotropic nystagmus is a prolonged postrotatory nystagmus after his head movement in the supine position due to the brain lesion involving the velocity storage mechanisms.     

Placido disk-based topography versus high-resolution rotating Scheimpflug camera for corneal power measurements in keratoconic and post-LASIK eyes: reliability and agreement

AIM: To compare the repeatability/reproducibility of measurement by high-resolution Placido disk-based topography with that of a high-resolution rotating Scheimpflug camera and assess the agreement between the two instruments in measuring corneal power in eyes with keratoconus and post-laser in situ keratomileusis (LASIK). METHODS: One eye each of 36 keratoconic patients and 20 subjects who had undergone LASIK was included in this prospective observational study. Two independent examiners worked in a random order to take three measurements of each eye with both instruments. Four parameters were measured on the anterior cornea: steep keratometry (Ks), flat keratometry (Kf), mean keratometry (Km), and astigmatism (Ks-Kf). Intra-examiner repeatability and inter-examiner reproducibility were evaluated by calculating the within-subject standard deviation (Sw) the coefficient of repeatability (R), the coefficient of variation (CoV), and the intraclass correlation coefficient (ICC). Agreement between instruments was tested with the Bland-Altman method by calculating the 95% limits of agreement (95% LoA). RESULTS: In keratoconic eyes, the intra-examiner and inter-examiner ICC were >0.95. As compared with measurement by high-resolution Placido disk-based topography, the intra-examiner R of the high-resolution rotating Scheimpflug camera was lower for Kf (0.32 vs 0.88), Ks (0.61 vs 0.88), and Km (0.32 vs 0.84) but higher for Ks-Kf (0.70 vs 0.57). Inter-examiner R values were lower for all parameters measured using the high-resolution rotating Scheimpflug camera. The 95% LoA were -1.28 to +0.55 for Kf, -1.36 to +0.99 for Ks, -1.08 to +0.50 for Km, and -1.11 to +1.48 for Ks-Kf. In the post-LASIK eyes, the intra-examiner and inter-examiner ICC were >0.87 for all parameters. The intra-examiner and inter-examiner R were lower for all parameters measured using the high-resolution rotating Scheimpflug camera. The intra-examiner R was 0.17 vs 0.88 for Kf, 0.21 vs 0.88 for Ks, 0.17 vs 0.86 for Km, and 0.28 vs 0.33 for Ks-Kf. The inter-examiner R was 0.09 vs 0.64 for Kf, 0.15 vs 0.56 for Ks, 0.09 vs 0.59 for Km, and 0.18 vs 0.23 for Ks-Kf. The 95% LoA were -0.54 to +0.58 for Kf, -0.51 to +0.53 for Ks and Km, and -0.28 to +0.27 for Ks-Kf. CONCLUSION: As compared with Placido disk-based topography, the high-resolution rotating Scheimpflug camera provides more repeatable and reproducible measurements of Ks, Kf and Ks in keratoconic and post-LASIK eyes. Agreement between instruments is fair in keratoconus and very good in post-LASIK eyes.     

利用数码相机测定面部皮肤颜色的初步研究

目的:利用数码相机进行面部皮肤颜色测定的可行性与合理性的研究.方法:在进行颜色采集之前,首先测定实验光源的稳定性.使用Canon EOS 20D单反数码相机,在实验光源稳定的时间内,以相同的拍摄参数(快门1/25 s,光圈4.5 自定义白平衡,ISO 800)采集122 例22～32 岁受试人群颌面部的皮肤颜色,拍摄文档保存为Jpeg格式.图像经Adobe photoshop7.0统一校色后,拾取皮肤CIE L*a*b*色度学空间颜色数据,利用SPSS 10.0做统计描述.结果:实验光源在21～70 min内是稳定的,可以达到比色要求.实验测得皮肤的L*a*b*色度学参数范围为:L* 49～66,a* 7～18,b* 5～22.结论:面部皮肤色度参数与测色手段和方式密切相关,数码相机作为面部赝复体的比色方法,在面部皮肤色彩信息全面采集、色彩信息准确传递方面,具有独特优势.     

Fatigue Damage Evaluation of Short Carbon Fiber Reinforced Plastics Based on Thermoelastic Temperature Change and Second Harmonic Components of Thermal Signal

Short fiber reinforced plastics (SFRPs) have excellent moldability and productivity compared to continuous fiber composites. In this study, thermoelastic stress analysis (TSA) was applied to detect delamination defects in short carbon fiber reinforced plastics (SCFRPs). The thermoelastic temperature change ΔT_E, phase of thermal signal θ_E, and second harmonic temperature component ΔT_D were measured. In the fatigue test of SCFRP, it was confirmed that changes in ΔT_E, θ_E, and ΔT_D appeared in the damaged regions. A staircase-like stress level test for a SCFRP specimen was conducted to investigate the generation mechanism of the ΔT_D. The distortion of the temperature change appeared at the maximum tension stress of the sinusoidal load—and when the stress level decreased, the temperature change returned to the original sinusoidal waveform. ΔT_D changed according to the change in the maximum stress during the staircase-like stress level test, and a large value of ΔT_D was observed in the final ruptured region. A distortion of the temperature change and ΔT_D was considered to be caused by the change in stress sharing condition between the fiber and resin due to delamination damage. Therefore, ΔT_D can be applied to the detection of delamination defects and the evaluation of damage propagation.     

高速涡轮牙钻及微创拔牙刀在阻生智齿拔除术中的应用效果

目的 探究高速涡轮牙钻及微创拔牙刀在阻生智齿拔除术中的应用效果。方法 选取2016年12月至2017年12月行阻生智齿拔除术的患者70例，根据拔牙方法将患者分为对照组（35例）与微创组（35例），对照组采取常规拔牙方法，微创组采取高速涡轮牙钻及微创拔牙刀拔牙。比较两组的手术指标（拔牙完整性、张口受限度、肿胀度、手术时间）、疼痛程度、并发症发生情况和术后生活质量（心理职能、生理功能、躯体疼痛、活力）。结果 微创组患者的拔牙完整性、张口受限度、肿胀度、手术时间4项手术指标均优于对照组（P均<0.05）。微创组和对照组患者治疗前的疼痛视觉模拟量表（VAS）评分差异无统计学意义（P>0.05），治疗后微创组VAS评分较对照组下降（P<0.05）。微创组并发症总发生率为11.43%（4/35），低于对照组[34.29%（12/35），P<0.05]。微创组术后3个月的心理职能等生活质量各项评分均高于对照组（P均<0.05）。结论 阻生智齿拔除术中应用高速涡轮牙钻及微创拔牙刀可有效提高治疗效果、减少并发症发生。     

抗——SOD单抗快速一步测定法的建立应用研究

目的　探讨抗—SOD单抗快速一步测定法的价值。方法　通过对反应温度的选择 ,建立抗—SOD快速一步测定法测定正常人群、糖尿病患者、恶性肿瘤患者及脑梗死患者的SOD含量。结果　ELISA快速一步测定法与常规ELISA测定法的结果相比具有良好的相关性 (r =0 993 ) ;正常对照组SOD含量随年龄的增长而增高 ;疾病组SOD含量与正常对照组相比具有显著性差异 (P值 <0 .0 5)。结论　快速一步测定法优于常规ELISA测定法。     

一阶导数高速脉冲极谱法用于盐酸普鲁卡因的定量分析

研究了一阶导数高速脉冲极谱法,并运用于盐酸普鲁卡因及其注射制剂的定量分析。在-0.04 V(对 Ag/AgCl)处出现的良好导数峰,于1.0～6.0×10~(-4)mol/L 范围内,导数峰电流与浓度呈线性关系。检测限为3.0×10~(-8)mol/L。操作简便、快速、灵敏,结果准确。     

~(99m)TC涎腺显像的临床评价(附43例报告)

在本组43例~(99m)Tc 涎腺显像中(25例良性肿瘤,12例恶性肿瘤,5例慢性腮腺炎及1例结核性腮腺淋巴结炎),42例腮腺及1例颁下腺均显示在涎腺显像图中.照相显像均显示了良性或恶性涎腺肿瘤的大小、范围及部位,无假阴性.相比之下,涎腺造影有3例假阴性.本文表明虽然~(99m)Tc 涎腺显像对腮腺Warthin 瘤无特异性,不能鉴别涎腺良、恶性肿瘤,但该检查是一种安全而简单的诊断技术,且比常规涎腺造影敏感.与涎腺造影对照有助于炎症与肿瘸、良性肿瘤与恶性肿瘤的鉴别.     

A new flood phantom to measure homogeneity of gamma cameras and to correct SPECT studies

A new flood phantom is presented. It combines patient like emission spectra, homogeneous activity distribution, and mechanical stability.Its properties and easy handling makes it the flood phantom of choice for measuring the homogeneity of a gamma camera or for correcting SPECT studies.     

宣威乌头生物碱的高速逆流层析分离法

利用高速逆流层析法以氯仿-甲醇-pH 4.3枸橼酸/磷酸二氢钠缓冲液(4:3:2)分离宣威乌头生物碱,可使九种生物碱得到良好分离。